The Autoimmune RESET

Vitiligo, Oxidative Stress & the Immune System: What Your Skin Is Telling You

VJ Hamilton Episode 171

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In this episode, we’re uncovering the hidden complexity behind a condition often dismissed as purely cosmetic: vitiligo.

Join VJ Hamilton, registered nutritionist and autoimmune health specialist, as we explore why pigment loss in the skin is actually a sign of deeper immune dysregulation—and what the latest science reveals about how to restore balance from the inside out.

You’ll discover:

  • What vitiligo is and why it’s more than a skin-deep issue
  • The immune pathways involved in melanocyte destruction, including the IFN-γ/CXCL10 feedback loop
  • How oxidative stress, low catalase activity, and mitochondrial dysfunction drive pigment loss
  • The link between vitiligo and other autoimmune conditions like Hashimoto’s, coeliac disease, and type 1 diabetes
  • Why emotional stress, trauma, and H. pylori infections may trigger or worsen symptoms
  • The truth about blueberries, hydroquinone, and whether antioxidant-rich foods should really be avoided
  • How greying hair, mitochondrial dysfunction, and skin pigmentation are all connected
  • Functional strategies for re-pigmentation including nutritional therapy, antioxidant support, and gut healing
  • The role of UVB light, nervous system regulation, and tools like Metabolomix+ testing to personalise your approach

Resources Mentioned in the Episode

🧪 Explore Metabolomix+ Testing – A functional test that assesses oxidative stress, nutrient status, and detox pathways to help uncover what’s driving melanocyte damage. You can learn more here

🧠 Explore Nurosym – A non-invasive vagus nerve stimulation device to support nervous system balance and reduce immune overactivation. Use code VH5 for 5% off at checkout.

🌿 Learn more about the gut–skin–immune axis and why supporting digestion is key for skin health.

💡 Join The Autoimmune Forum – A free community where you can connect with others navigating vitiligo, Hashimoto’s, and other immune-driven conditions.

Perfect for you if:

  • You have vitiligo and are looking for more than topical treatments or steroids
  • You’ve noticed premature greying, fatigue, or nutrient deficiencies alongside pigment changes
  • You’re interested in how stress, diet, gut health, and immune function interact
  • You want a science-backed, compassionate, and holistic approach to re-pigmentation

The information shared in this episode is for educational purposes only and is not intended to replace medical advice. Always consult your healthcare provider before making changes to your medications, supplements, or treatment plan—especially if you have a diagnosed autoimmune condition.

Some resources or products mentioned in this episode may include affiliate links. This means I may earn a small commission if you choose to purchase through them—at no additional cost to you. I only recommend tools and products I believe in and use with clients.

Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.

Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.