The Autoimmune RESET
VJ Hamilton is a nutritionist, scientist, and autoimmune disease expert who founded The Autoimmunity Nutritionist Clinic, a Nutritional Therapy and Functional Medicine clinic specialising in autoimmune disease.
VJ combines her lived experience overcoming autoimmune disease symptoms with her knowledge of nutrition, health, biochemistry, and immunology to provide you with the most up-to-date research on autoimmune disease.
The Autoimmune RESET aims to provide you with the education and resources to empower you to take steps to transform your health and feel better than ever.
In each episode, VJ will share simple ways to uplevel your diet and lifestyle, key learnings from her own journey reversing autoimmune disease, and inspirational stories from those who have reset their autoimmune symptoms and are now thriving in life.
Health practitioners, mind and body experts, and scientists will be joining VJ as guests on the show, as well as those who have inspirational stories to share and are now thriving in everyday life!
And don't miss the short episodes every Friday, The Friday 5, in which VJ shares five healthy must-haves for you to explore over the weekend.
The Autoimmune RESET
Endometriosis Root Causes: The Nervous System, Hormones & Immune Connection Explained
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In this episode, I explore a more integrative and systems-based understanding of endometriosis — moving beyond the conventional narrative of it being “just a hormonal condition” or “just about pain.”
Drawing on emerging research and what I see daily in clinic, I introduce the neuroendocrine–immune axis — the dynamic relationship between the nervous system, hormones, and immune system — and explain why this interconnected network is key to understanding both the development and persistence of endometriosis.
We look at why symptoms don’t always match what is seen clinically, why inflammation can become chronic, and why the body may struggle to clear endometrial tissue effectively. I also discuss the role of the vagus nerve, immune dysfunction, oestrogen metabolism, and the gut microbiome — including the relevance of beta-glucuronidase and how this is assessed in clinical practice.
This episode is designed to help you make sense of your symptoms, feel validated in your experience, and begin to approach endometriosis in a more holistic and empowering way.
What You’ll Learn
- Why endometriosis is not just a hormonal or pain condition
- What the neuroendocrine–immune axis is — explained simply
- How the nervous system influences inflammation, hormones, and immune function
- The role of the vagus nerve and why vagal tone matters
- Why inflammation in endometriosis often becomes chronic
- How immune dysfunction contributes to the persistence of endometrial tissue
- The concept of retrograde menstruation — and why it doesn’t explain everything
- How the gut microbiome influences oestrogen balance
- What beta-glucuronidase is and why it matters in endometriosis
- How testing (such as the GI Effects stool test) can provide deeper insight
- Why symptoms like fatigue, IBS, and heightened sensitivity are often connected
- Practical ways to begin supporting your body today
🧠 Looking to support inflammation more effectively?
→ I often use and recommend specialised pro-resolving mediators (SPMs), such as Resolvin, to support the body’s ability to actively resolve inflammation — not just suppress it.
You can explore it here:
→ UK: BodyBio UK Resolvin (code AUTOIMMUNITY for 15% discount at checkout)
→ US: BodyBio US Resolvin (code VJ15 for 15% discount at checkout)
As always, speak to your practitioner to ensure this is appropriate for you.
🧘♀️ Need nervous system support?
→ I personally use and recommend Nurosym, a vagus nerve stimulation device clinically shown to support immune balance, inflammation, and stress recovery.
Use this link: https://link.nurosym.com/VJ10 for 10% discount at checkout.
📥 New to the podcast or need a starting point?
→ Download my free The Autoimmunity Recovery Plan
— a simple guide that outlines the steps I recommend to all clients as they begin calming the immune response and rebuilding resilience.
The information shared in this episode is for educational purposes only and is not intended to replace medical advice. Always consult your healthcare provider.
Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.